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ALK inhibitor 1

CAS No. 761436-81-1

ALK inhibitor 1( —— )

Catalog No. M26052 CAS No. 761436-81-1

ALK inhibitor 1 is a selective ALK kinase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ALK inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    ALK inhibitor 1 is a selective ALK kinase inhibitor.
  • Description
    ALK inhibitor 1 is a selective ALK kinase inhibitor.(In Vitro):ALK inhibitor 1 inhibits IGF-1R.
  • In Vitro
    ALK inhibitor 1 (compound 17) inhibits IGF-1R with an IC50 of 90 nM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    FAK
  • Recptor
    Glucocorticoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    761436-81-1
  • Formula Weight
    562.49
  • Molecular Formula
    C23H28BrN7O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?1M HCl : 100 mg/mL (177.78 mM)
  • SMILES
    CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Torres MP, Entwistle F, Coote PJ. Effective immunosuppression with dexamethasone phosphate in the Galleria mellonella larva infection model resulting in enhanced virulence of Escherichia coli and Klebsiella pneumoniae. Med Microbiol Immunol. 2016 Aug;205(4):333-43. doi: 10.1007/s00430-016-0450-5. PubMed PMID: 26920133; PubMed Central PMCID: PMC4939170.
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